RelationshipBetweenOverweight and ObesityWith Hospitalization for Heart Failure in20,985PatientsWith Type1 Diabetes A population-based study from the Swedish National Diabetes Registry

RESULTSdIn a sample of 20,985 type 1 diabetic patients (mean age, 38.6 years; mean BMI, 25.0 kg/m), 635 patients were hospitalized with HF as a primary or secondary diagnosis during a median follow-up of 9.1 years. Cox regression adjusting for age, sex, diabetes duration, smoking, HbA1c, systolic and diastolic blood pressures, and baseline and intercurrent comorbidities (including myocardial infarction) showed a significant relationship between BMI and hospitalization for HF (P, 0.0001). In reference to patients in the BMI 20–25 kg/m category, hazard ratios (HRs) were as follows: HR 1.22 (95% CI, 0.83–1.78) for BMI,20 kg/m; HR 0.94 (95% CI 0.78–1.12) for BMI 25–30 kg/m; HR 1.55 (95% CI, 1.20–1.99) for BMI 30–35 kg/m; and HR 2.90 (95% CI, 1.92–4.37) for BMI $35 kg/m.